Phenotype Image Detail

Image

Caption

A, in situ hybridization analysis of trophoblast-specific protein-alpha mRNA in control Nrk^tm1Mkom/Nrk⁺ (XX^Nrk) and Nrk^tm1Mkom/Nrk^tm1Mkom (X^NrkX^Nrk) placentas at 18.5 dpc. B; immunofluorescence staining of Ki67 protein in control and mutant placentas at 14.5 dpc. Cryosections were stained with anti-Ki67 antibody (green) and phalloidin (magenta). Merged images are also shown (right). D, decidual layer; S, spongiotrophoblast layer; L, labyrinth layer. Bars, 1 mm (A) and 100 um (B).

Copyright

This image is from Denda K, J Biol Chem 2011 Aug 19;286(33):28802-10 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:175907

Associated Alleles

Symbol	Name
Nrk^tm1Mkom	Nik related kinase; targeted mutation 1, Masayuki Komada

Associated Genotypes

Allelic Composition	Genetic Background
Nrk^tm1Mkom/Nrk^tm1Mkom	B6.129S4-Nrk^tm1Mkom