Phenotype Image Detail

Image

Caption

At 8 weeks of age wild-type (WT) mice exhibit clear lenses (A) in contrast to total cataracts observed in Srebf2^lop13/Srebf2^lop13 eyes (B). Histological analysis of lens sections from WT lenses (C) revealed highly organized fiber cells while swollen fiber cells (arrow) and bladder cells (arrowhead) were identified in mutant lenses (D). At the posterior of the mutant lenses (F) morgagnian globules and liquefied lens material (asterisk) were noted. Clear and organized lens structures were observed in WT lenses (E).

Copyright

This image is from Merath KM, Mamm Genome 2011 Aug 21;(): and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:176249

Associated Alleles

Symbol	Name
Srebf2^lop13	sterol regulatory element binding factor 2; lens opacity 13

Associated Genotypes

Allelic Composition	Genetic Background
Srebf2^lop13/Srebf2^lop13	STOCK Srebf2^lop13/J