Phenotype Image Detail

Image

Caption

(A-H) External views of control (A, C, E, and G) and mutant (B, D, F, and H; Rdh10^tm2Ics line) embryos. (I-P) Histological analysis (hematoxylin/eosin staining) of control (I, K, M, and O) and Rdh10^tm2Ics/Rdh10^tm2Ics (J, L, N, and P) embryos. Frontal sections at the level of the eyes (I and J), heart (K and L; Insets show the aortico-pulmonary/arterial trunk), lungs (M and N; these are absent in the mutant), and abdomen (O and P; Insets show the kidney). Ao, aorta; DR, dorsal retina; Ey, eye; Ki, kidney; FL, forelimb; HL, hindlimb; Li, liver; Lu, lung; LV, left ventricle; OS, optic stalk; Pa, pancreas; PT, pulmonary trunk; RV, right ventricle; St, stomach; TA, truncus arteriosus; VR, ventral retina.

Copyright

This image is from Rhinn M, Proc Natl Acad Sci U S A 2011 Oct 4;108(40):16687-92. Copyright 2011 National Academy of Sciences, U.S.A. J:177362

Associated Alleles

Symbol	Name
Rdh10^tm2Ics	retinol dehydrogenase 10 (all-trans); targeted mutation 2, Mouse Clinical Institute

Associated Genotypes

Allelic Composition	Genetic Background
Rdh10^tm2Ics/Rdh10^tm2Ics	Not Specified