Phenotype Image Detail

Image

Caption

Mutant 449-005-1 (E16.5) exhibit interrupted aortic arch (IAA) and malalignment of the great arteries, which was shown to be double outlet right ventricle (DORV) by EFIC analysis.

Copyright

This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213

Associated Alleles

Symbol	Name
Tab1^b2b449Clo	TGF-beta activated kinase 1/MAP3K7 binding protein 1; Bench to Bassinet Program (B2B/CVDC), mutation 449 Cecilia Lo

Associated Genotypes

Allelic Composition	Genetic Background
Tab1^b2b449Clo/Tab1^b2b449Clo	C57BL/6J-Tab1^b2b449Clo