Phenotype Image Detail

Image

Caption

(C and D) Anatomical analysis of Gata5^tm1.2Nemr/Gata5^tm1.2Nemr (Gata5^-/-) mice revealed the presence of bicuspid aortic valve and tricuspid aortic valve. Arrows indicate the point of attachment of the valve cups to the aortic wall. (E and F) Trichrome staining of the aortic valve of the mutant mice, showing the presence of 2 or 3 leaflets (asterisks). Scale bars: 500 um. *P < 0.05, **P < 0.01.

Copyright

This image is from Laforest B, J Clin Invest 2011 Jul 1;121(7):2876-87 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:175663

Associated Alleles

Symbol	Name
Gata5^tm1.2Nemr	GATA binding protein 5; targeted mutation 1.2, Mona Nemer

Associated Genotypes

Allelic Composition	Genetic Background
Gata5^tm1.2Nemr/Gata5^tm1.2Nemr	involves: 129 * C57BL/6