Phenotype Image Detail

Image

Caption

(A-D) Anatomical analysis of wild-type and Gata5^tm1.2Nemr/Gata5^tm1.2Nemr mice. (A and B) Frontal view orientation of the hearts showed a mild increase in Gata5^tm1.2Nemr/Gata5^tm1.2Nemr mouse heart size. (C and D) Trichrome staining demonstrated increased heart size, right atrial enlargement, and increased left ventricle internal dimension of the mutant mice. LA, left atrium; RA, right atrium. (E and F) High-magnification views of cardiomyocytes, showing increased cell size in the mutant mice.

Copyright

This image is from Laforest B, J Clin Invest 2011 Jul 1;121(7):2876-87 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:175663

Associated Alleles

Symbol	Name
Gata5^tm1.2Nemr	GATA binding protein 5; targeted mutation 1.2, Mona Nemer

Associated Genotypes

Allelic Composition	Genetic Background
Gata5^tm1.2Nemr/Gata5^tm1.2Nemr	involves: 129 * C57BL/6