Phenotype Image Detail

Image

Caption

(C) Mouse spleen weight in Tg(Mx1-cre)1Cgn/0 controls (Ptpn11^+/+/Mx1-Cre⁺), Ptpn11^tm1Ckq/Ptpn11⁺ Tg(Mx1-cre)1Cgn/0 mice (Ptpn11^E76K/+/Mx1-Cre+), and Ptpn11^tm1Ckq/Ptpn11⁺ (Ptpn11^E76Kneo/+Mx1-Cre^-) mice was quantified 6-8 weeks after pl-pC treatment (n = 8 per group). Bar, 5 mm.

Copyright

This image is from Xu D, J Exp Med 2011 Sep 26;208(10):1977-88, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:177285

Associated Alleles

Symbol	Name
Ptpn11^tm1Ckq	protein tyrosine phosphatase, non-receptor type 11; targeted mutation 1, Cheng-Kui Qu
Tg(Mx1-cre)1Cgn	transgene insertion 1, University of Cologne

Associated Genotypes

Allelic Composition	Genetic Background
Ptpn11^tm1Ckq/Ptpn11^+ Tg(Mx1-cre)1Cgn/0	involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA