Phenotype Image Detail

Image

Caption

Iris phenotype of Foxf2^W174R/Foxf2⁺ mice. The iris in wild-type mice (+/+) consists of a robust upper stromal layer (arrowhead) and a lower pigmented epithelium (arrow). The stroma in three heterozygous Foxf2^W174R/Foxf2⁺ (m/+) mice is flattened or atrophic. The bottom image shows variable thickness across the iris tissue in both stromal and epithelial layers. Scale bar = 40 um.

Copyright

This image is from McKeone R, PLoS One 2011;6(10):e25489, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:178103

Associated Alleles

Symbol	Name
Foxf2^W174R	forkhead box F2; Trp174Arg

Associated Genotypes

Allelic Composition	Genetic Background
Foxf2^W174R/Foxf2^+	involves: BALB/c * C3H/HeH