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Caption | Iridocorneal phenotypic features in Foxf2W174R/Foxf2+ mice. (A) In wild-type mice, Schlemm's canal extends between the two white arrows. The trabecular meshwork is indicated by an asterisk. The ciliary body (CB) and ciliary body process (CBP) extend into the anterior chamber. The ciliary muscle is indicated by the black arrow. Iris Normal iridocorneal angle (A) indicated by double-headed arrow. (B-E) Phenotype in heterozygous Foxf2W174R/Foxf2+ mice. All mice had shortened or absent Schlemm's canal and a hypoplastic CB or CBP. (C), Trabecular meshwork is hypoplastic and the iris is parallel to the cornea (no angle). (E), Trabecular meshwork is hypoplastic and iridocorneal adhesion (arrowhead) is present. Scale bar = 50 um. | ||||
Copyright | This image is from McKeone R, PLoS One 2011;6(10):e25489, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:178103 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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