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Caption | Representative images of eye phenotype of aged heterozygous Foxf2W174R/Foxf2+ mutant mice. A, 6 month old Foxf2W174R/Foxf2+ eye (m+/) showing normal retinal termination at the edge of the optic nerve fibre layer (black arrows). B&C, sections through two other 6 month old Foxf2W174R/Foxf2+ eyes showing abnormal bulge in the nerve fibre layer. The outer nuclear layer of the retina can be seen to continue at the surface of this bulging tissue (white arrows). D&E, retinal sections in 6 month eyes. F&G, corneal sections in 6 month eyes. H-J, 12 month Foxf2W174R/Foxf2+ optic nerves that do not show signs of glaucomatous change. v, vein; p, photoreceptors; onl, outer nuclear layer; inl, inner nuclear layer; ce, corneal epithelium; cs, corneal stroma. Scale bar = 50 um. | ||||
Copyright | This image is from McKeone R, PLoS One 2011;6(10):e25489, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:178103 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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