Phenotype Image Detail

Image

Caption

(C) Uterine estrogen receptor alpha (ERalpha) immunohistochemistry of 8-week-old representative mice. (D) Morphology of Esr1^tm3.1Ksk/Esr1^tm3.1Ksk (AF2ER (KI/KI)) female reproductive organs in the 8-week-old representative mice. (E) Histology of 8-week-old representative mutant female mice. Uterine (top) and ovarian (middle) tissue H&E staining from wild-type (WT (+/+), left) and homozygous mutant (right) mice. (Scale bar: 100 um.) Mammary gland (bottom) whole-mount Carmine alum staining from 8-week-old representative mice. (Scale bar: 1 cm.)

Copyright

This image is from Arao Y, Proc Natl Acad Sci U S A 2011 Sep 6;108(36):14986-91. Copyright 2011 National Academy of Sciences, U.S.A. J:176459

Associated Alleles

Symbol	Name
Esr1^tm3.1Ksk	estrogen receptor 1 (alpha); targeted mutation 3.1, Kenneth S Korach

Associated Genotypes

Allelic Composition	Genetic Background
Esr1^tm3.1Ksk/Esr1^tm3.1Ksk	involves: 129S6/SvEvTac * C57BL/6