Phenotype Image Detail

Image

Caption

(B) Uterine histology after vehicle (Veh), ICI182780 (ICI), tamoxifen (TAM), or estradiol (E2) (10 ug/kg) treatments for three consecutive days in representative Esr1^tm3.1Ksk/Esr1^tm3.1Ksk (AF2ER (KI/KI)) mice. ICI and TAM treatment increase the uterine wet weight of homozygous mice.

Copyright

This image is from Arao Y, Proc Natl Acad Sci U S A 2011 Sep 6;108(36):14986-91. Copyright 2011 National Academy of Sciences, U.S.A. J:176459

Associated Alleles

Symbol	Name
Esr1^tm3.1Ksk	estrogen receptor 1 (alpha); targeted mutation 3.1, Kenneth S Korach

Associated Genotypes

Allelic Composition	Genetic Background
Esr1^tm3.1Ksk/Esr1^tm3.1Ksk	involves: 129S6/SvEvTac * C57BL/6