Phenotype Image Detail

Image

Caption

(A) Crossing the Gt(ROSA)26Sor^{tm3(CAG-Il17a)Awai} allele to the delete-cre strain yields Gt(ROSA)26Sor^{tm3.1(CAG-Il17a)Awai}/Gt(ROSA)26Sor⁺ (Del-IL17^ind/+) mice. Skin inflammation, stunted growth, and failure to thrive is a consistent phenotype in all Gt(ROSA)26Sor^{tm3.1(CAG-Il17a)Awai}/Gt(ROSA)26Sor⁺ mice observed when compared with delete-cre littermate controls (Del).

Copyright

This image is from Haak S, J Clin Invest 2009 Jan;119(1):61-9 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:144710

Associated Alleles

Symbol	Name
Gt(ROSA)26Sor^tm3.1(CAG-Il17a)Awai	gene trap ROSA 26, Philippe Soriano; targeted mutation 3.1, Ari Waisman

Associated Genotypes

Allelic Composition	Genetic Background
Gt(ROSA)26Sor^tm3.1(CAG-Il17a)Awai/Gt(ROSA)26Sor^+	involves: BALB/c * C57BL/6