Phenotype Image Detail

Image

Caption

A-E, delay of pericyte coverage in area 2 of P7 Angptl4^tm1Vlcg/Angptl4^tm1Vlcg (angptl14^LacZ/LacZ) retinas. Representative images of P7 heterozygotes (angptl14^+/LacZ) (A and C) and homozygous mutants (B and D) retinas stained with isolectin B4 (IB4, red) and anti-chondroitin sulfate proteoglycan (NG2, green) (A-D). The arrows point to abnormal pericytes (B and D) on homozygous mutant capillaries. Scale bar = 25 um. E, shown is the ratio of pericytes (NG2 area) to endothelial cell surface (IB4 vessels), n = 6 per group. p < 0.005.

Copyright

This image is from Perdiguero EG, J Biol Chem 2011 Oct 21;286(42):36841-51 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:177790

Associated Alleles

Symbol	Name
Angptl4^tm1Vlcg	angiopoietin-like 4; targeted mutation 1, Velocigene

Associated Genotypes

Allelic Composition	Genetic Background
Angptl4^tm1Vlcg/Angptl4^tm1Vlcg	Not Specified