Phenotype Image Detail

Image

Caption

Periodic acid-Schiff and E-Cadherin (CDH1) staining of the lungs of wild-type (GAK-kd+/+) and Gak^tm1Noj/Gak^tm1Noj (GAK-kd-/-) pups. (A) Periodic acid-Schiff (PAS) positive signals obtained by standard methods using the PAS stain were detected in bronchial epithelial cells (closed arrowhead), alveolar lining cells (open arrowhead), and cells present in the inter-alveolar region (white asterisk). (B) E-Cadherin positive signals obtained by immunostaining with anti-E-Cadherin antibody were detected in bronchial epithelial cells (closed arrowhead), alveolar lining cells (open arrowhead), and cells present in the inter-alveolar region (black asterisk). Images were recorded using a microscope (BX51, Olympus) equipped with a CCD camera (DP72, Olympus). Bar = 50 um.

Copyright

This image is from Tabara H, PLoS One 2011;6(10):e26034, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179585

Associated Alleles

Symbol	Name
Gak^tm1Noj	cyclin G associated kinase; targeted mutation 1, Hiroshi Nojima

Associated Genotypes

Allelic Composition	Genetic Background
Gak^tm1Noj/Gak^tm1Noj	C57BL/6-Gak^tm1Noj