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Phenotype Image Detail
Image
Caption Keratinocyte-specific deletion of Smad2 results in accelerated re-epithelialization during wound healing. B, wound widths were determined by K14 (brown) immunostaining in Tg(KRT5-cre)1Xya/0 Smad2tm1Xya/Smad2tm1Xya (K5-Cre;Smad2fl/fl) and control (K5-Cre;Smad2fl/+) wounded skin at days 3, 5, and 7 after injury. Arrows indicated the leading edges of wounded epidermis.
Copyright This image is from Yang X, J Biol Chem 2011 Dec 9;286(49):42267-73 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:178733
Associated
Alleles
Symbol Name
Smad2tm1Xya SMAD family member 2; targeted mutation 1, Xiao Yang
Tg(KRT5-cre)1Xya transgene insertion 1, Xiao Yang
Associated
Genotypes
Allelic Composition Genetic Background
Smad2tm1Xya/Smad2tm1Xya
Tg(KRT5-cre)1Xya/0 		involves: 129S6/SvEvTac
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory