Phenotype Image Detail

Image

Caption

Keratinocyte-specific deletion of Smad2 results in accelerated re-epithelialization during wound healing. B, wound widths were determined by K14 (brown) immunostaining in Tg(KRT5-cre)1Xya/0 Smad2^tm1Xya/Smad2^tm1Xya (K5-Cre;Smad2^fl/fl) and control (K5-Cre;Smad2^fl/+) wounded skin at days 3, 5, and 7 after injury. Arrows indicated the leading edges of wounded epidermis.

Copyright

This image is from Yang X, J Biol Chem 2011 Dec 9;286(49):42267-73 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:178733

Associated Alleles

Symbol	Name
Smad2^tm1Xya	SMAD family member 2; targeted mutation 1, Xiao Yang
Tg(KRT5-cre)1Xya	transgene insertion 1, Xiao Yang

Associated Genotypes

Allelic Composition	Genetic Background
Smad2^tm1Xya/Smad2^tm1Xya Tg(KRT5-cre)1Xya/0	involves: 129S6/SvEvTac