Phenotype Image Detail

Image

Caption

(F) Microscopic image of H&E-stained tissue sections of lung (a and b), liver (c and d), and kidney (e and f) of wild-type (Tnip1+/+) and Tnip1^{Gt(E059E05)Wrst}/Tnip1^{Gt(E059E05)Wrst} (Tnip1-/-) mice. (Scale bar: 80 uM.) (G) Microscopic image of F4/80-stained tissue sections of lung (a and b), liver (c and d), and kidney (e and f). Brownish color identifies F4/80+ cells. (Scale bar: 80 uM). All experiments shown were done using 6- to 8-week-old sex-matched wild-type and Tnip1^{Gt(E059E05)Wrst}/Tnip1^{Gt(E059E05)Wrst} mice. Several parenchymatous organs, such as liver, lung, and kidneys, were infiltrated with leukocytes, primarily F4/80+ myeloid cells and neutrophils.

Copyright

This image is from Zhou J, Proc Natl Acad Sci U S A 2011 Nov 1;108(44):E998-1006. Copyright 2011 National Academy of Sciences, U.S.A. J:180054

Associated Alleles

Symbol	Name
Tnip1^Gt(E059E05)Wrst	TNFAIP3 interacting protein 1; gene trap E059E05, German Gene Trap Consortium

Associated Genotypes

Allelic Composition	Genetic Background
Tnip1^Gt(E059E05)Wrst/Tnip1^Gt(E059E05)Wrst	involves: 129P2/OlaHsd * C57BL/6