Phenotype Image Detail

Image

Caption

Reduced neuronal regeneration after perinatal hypoxic-ischemia (HI) in Neil3^tm1Bjor/Neil3^tm1Bjor (Neil3-/-) mice. (A and B) Infarction size calculated as reduction in the MAP2 immunoreactive area (brown) in the ipsilateral hemispheres as a percentage of the contralateral hemisphere at bregma 0.4. (Scale bars, 1 mm.) *P = 0.024. (C) Area loss in coronal sections extending from brain level 1-8. *P < 0.05. (D) Loss of volume calculated from 16 evenly spaced sections throughout the forebrain. *P = 0.029. (B-D) n = 5-6 mice per time point. Data represent mean +/- SEM.

Copyright

This image is from Sejersted Y, Proc Natl Acad Sci U S A 2011 Nov 15;108(46):18802-7. Copyright 2011 National Academy of Sciences, U.S.A. J:180177

Associated Alleles

Symbol	Name
Neil3^tm1Bjor	nei like 3 (E. coli); targeted mutation 1, Magnar Bjoras

Associated Genotypes

Allelic Composition	Genetic Background
Neil3^tm1Bjor/Neil3^tm1Bjor	involves: 129 * C57BL/6