Phenotype Image Detail

Image

Caption

(A) Lens from wild-type (WT) 10-month-old mouse with normal fiber cells near the lens surface and normal appearing fibers. (B) Large swollen cells and gaps between fiber cells in lens from 10-month-old Cryaa^tm1Ady/Cryaa^tm1Ady (R49Cneo/R49Cneo) mouse. (C) The swollen fiber cells increased in both size and number with increased age, and extended towards the center of the lens. The number of swollen cells per lens section is shown.

Copyright

This image is from Andley UP, BMC Ophthalmol 2009;9():4, an open-access article, licensee BioMed Central Ltd. J:157274

Associated Alleles

Symbol	Name
Cryaa^tm1Ady	crystallin, alpha A; targeted mutation 1, Usha P Andley

Associated Genotypes

Allelic Composition	Genetic Background
Cryaa^tm1Ady/Cryaa^tm1Ady	involves: 129