Phenotype Image Detail

Image

Caption

Anallysis of cortical fiber cell membranes. Lens sections were stained with haematoxylin/eosin. (A) Normal appearance of fiber cells in the lens equatorial region in 3-week-old wild-type lenses. (B) Swollen fiber cels and separations between fiber cells in 3-week-old Cryaa^tm1Ady/Cryaa⁺ heterozygous lenses. (C) Gaps between fiber cells in 3-week-old mutant homozygous Cryaa^tm1Ady/Cryaa^tm1Adylenses.

Copyright

This image is from Andley UP, BMC Ophthalmol 2009;9():4, an open-access article, licensee BioMed Central Ltd. J:157274

Associated Alleles

Symbol	Name
Cryaa^tm1Ady	crystallin, alpha A; targeted mutation 1, Usha P Andley

Associated Genotypes

Allelic Composition	Genetic Background
Cryaa^tm1Ady/Cryaa^tm1Ady	involves: 129
Cryaa^tm1Ady/Cryaa^+	involves: 129