Phenotype Image Detail

Image

Caption

Ror1^tm1.2Meg/Ror1^tm1.2Meg Ror2^tm1.2Meg/Ror2^tm1.2Meg embryos exhibit morphogenesis defects. (A-B) Representative images of unfixed E12.5 control Ror1^tm1.2Meg/Ror1⁺ Ror2^tm1.2Meg/Ror2⁺ (Ror1^+/-; Ror2^+/-)embryo (A). Ror1^tm1.2Meg/Ror1^tm1.2Meg Ror2^tm1.2Meg/Ror2^tm1.2Meg (Ror1^-/-; Ror2^-/-) embryo (B).

Copyright

This image is from Ho HY, Proc Natl Acad Sci U S A 2012 Mar 13;109(11):4044-51. Copyright 2012 National Academy of Sciences, U.S.A. J:182150

Associated Alleles

Symbol	Name
Ror1^tm1.2Meg	receptor tyrosine kinase-like orphan receptor 1; targeted mutation 1.2, Michael E Greenberg
Ror2^tm1.2Meg	receptor tyrosine kinase-like orphan receptor 2; targeted mutation 1.2, Michael E Greenberg

Associated Genotypes

Allelic Composition	Genetic Background
Ror1^tm1.2Meg/Ror1^tm1.2Meg Ror2^tm1.2Meg/Ror2^tm1.2Meg	involves: 129S4/SvJae * C57BL/6 * FVB/N