Phenotype Image Detail

Image

Caption

Murine ABHD5 (CGI-58) deficiency causes neutral lipid storage disease (NLSD) with ichthyosis. A, Photograph of newborn wild-type and Abhd5^tm1.1Rze/Abhd5^tm1.1Rze (Cgi-58-/-) mice. Note the glossy dry skin, the smaller size of the body, and necrotic tail tip.

Copyright

This image is from Radner FP, J Biol Chem 2010 Mar 5;285(10):7300-11 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160725

Associated Alleles

Symbol	Name
Abhd5^tm1.1Rze	abhydrolase domain containing 5; targeted mutation 1.1, Rudolf Zechner

Associated Genotypes

Allelic Composition	Genetic Background
Abhd5^tm1.1Rze/Abhd5^tm1.1Rze	involves: 129P2/OlaHsd * C57BL/6