Phenotype Image Detail

Image

Caption

A, uptake of Evans blue dye (EBD) in the hearts of Capns1^tm1.1Otsu/Capns1^tm1.1Otsu Tg(Myh6-cre)2182Mds/0 (Capns1-/-) and control Capns1^tm1.1Otsu/Capns1^tm1.1Otsu (Capns1+/+) mice following transverse aortic constriction (TAC) or sham operation. B, EBD-positive area per LV cross-sectional area in TAC-operated homozygous mutant (n = 6) and control (n = 4) mice. Values are expressed as the mean +/-S.E. *, p<0.05.

Copyright

This image is from Taneike M, J Biol Chem 2011 Sep 16;286(37):32170-7 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:176736

Associated Alleles

Symbol	Name
Capns1^tm1.1Otsu	calpain, small subunit 1; targeted mutation 1.1, Kinya Otsu
Tg(Myh6-cre)2182Mds	transgene insertion 2182, Michael D Schneider

Associated Genotypes

Allelic Composition	Genetic Background
Capns1^tm1.1Otsu/Capns1^tm1.1Otsu Tg(Myh6-cre)2182Mds/0	involves: C57BL/6J * FVB/N