Phenotype Image Detail

Image

Caption

Hcrt (orexin-A) immunohistochemical staining of the dorsomedial hypothalamic nucleus (A) and the lateral hypothalamic nucleus (B) of heterozygous (Hap1^tm2Xjl/Hap1⁺ Tg(HCRT-cre)1Stak/0; Orexin-Hap1^+/-) and Hap1^tm2Xjl/Hap1^tm2Xjl Tg(HCRT-cre)1Stak/0 (Orexin-Hap1^-/-) mice. Low (X20, upper panels) and high (X65, lower panels) magnification images showing fragmented neurites of orexin neurons in homozygous mice. Scale bars, 10 um.

This image is from Lin YF, J Biol Chem 2010 May 21;285(21):15941-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:163896

Associated
Alleles

Symbol	Name
Hap1^tm2Xjl	huntingtin-associated protein 1; targeted mutation 2, Xiao-Jiang Li
Tg(HCRT-cre)1Stak	transgene insertion 1, Takeshi Sakurai

Associated
Genotypes

Allelic Composition	Genetic Background
Hap1^tm2Xjl/Hap1^tm2Xjl Tg(HCRT-cre)1Stak/0	involves: 129 * C57BL/6 * DBA/1

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