Phenotype Image Detail

Image

Caption

Detection of BrdU-positive S-phase epithelial cells in the pyloric mucosa of wild-type (+/+) and A4gnt^tm1Jnaka/A4gnt^tm1Jnaka (-/-) mice. (A) Comparison of the number of BrdU-positive, S-phase epithelial cells in the pyloric mucosa of wild-type and A4gnt^tm1Jnaka/A4gnt^tm1Jnaka mice at different ages. Each group consists of 6 mice, and data represent the mean +/- SEM. **P < 0.01. (B) Comparison of the BrdU-labeling index between wild-type and mutant mice. Each group consists of 6 mice, and data represent the mean +/- SEM, *P < 0.05; **P < 0.01. (C) Localization of S-phase cells in pyloric mucosa. Scale bar: 100 um.

Copyright

This image is from Karasawa F, J Clin Invest 2012 Mar 1;122(3):923-34 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184485

Associated Alleles

Symbol	Name
A4gnt^tm1Jnaka	alpha-1,4-N-acetylglucosaminyltransferase; targeted mutation 1, Jun Nakayama

Associated Genotypes

Allelic Composition	Genetic Background
A4gnt^tm1Jnaka/A4gnt^tm1Jnaka	B6.129S6-A4gnt^tm1Jnaka