Phenotype Image Detail

Image

Caption

(A) Inflammation score for mononuclear cell infiltration in the antrum of A4gnt^tm1Jnaka/A4gnt^tm1Jnaka (-/-) mice. Each group consists of 6 mice, and data represent the mean +/- SEM. *P < 0.05; **P < 0.01. (B) Inflammation score for neutrophil infiltration in the antrum of mutant mice. Each group consists of 6 mice, and data represent the mean +/- SEM. *P < 0.05; **P < 0.01. (C) Detection of F4/80-positive macrophages in gastric mucosa. Immunohistochemistry with anti-F4-80 antibody (left panel). Scale bar: 50 um. Comparison of number of F4/80-positive macrophages in gastric mucosa of wild-type and mutant mice (right panel). Each group consists of 6 mice, and data represent the mean +/- SEM. **P < 0.01. (D) Detection of CD31-positive endothelial cells in gastric mucosa. Immunohistochemistry with anti-CD31 antibody (left panel). Scale bar: 50 um. Comparison of number of CD31-positive endothelial cells in gastric mucosa of wild-type and mutant mice (right panel). Each group consists of 6 mice, and data represent the mean +/- SEM. **P < 0.01.

Copyright

This image is from Karasawa F, J Clin Invest 2012 Mar 1;122(3):923-34 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184485

Associated Alleles

Symbol	Name
A4gnt^tm1Jnaka	alpha-1,4-N-acetylglucosaminyltransferase; targeted mutation 1, Jun Nakayama

Associated Genotypes

Allelic Composition	Genetic Background
A4gnt^tm1Jnaka/A4gnt^tm1Jnaka	B6.129S6-A4gnt^tm1Jnaka