Phenotype Image Detail

Image

Caption

Representative en face and root section images. Representative Sudan IV stained aortas (A) and oil red O stained aortic root sections (B) from Ldlr^tm1Her/Ldlr^tm1Her Nr1h3^tm1.1Djm/Nr1h3^tm1.1Djm and Ldlr^tm1Her/Ldlr^tm1Her Nr1h3^tm1.1Djm/Nr1h3^tm1.1Djm Speer6-ps1^{Tg(Alb-cre)21Mgn}/0 mice

Copyright

This image is from Zhang Y, J Clin Invest 2012 May 1;122(5):1688-99 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184536

Associated Alleles

Symbol	Name
Ldlr^tm1Her	low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Nr1h3^tm1.1Djm	nuclear receptor subfamily 1, group H, member 3; targeted mutation 1.1, David J Mangelsdorf
Speer6-ps1^Tg(Alb-cre)21Mgn	spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson

Associated Genotypes

Allelic Composition	Genetic Background
Ldlr^tm1Her/Ldlr^tm1Her Nr1h3^tm1.1Djm/Nr1h3^tm1.1Djm Speer6-ps1^Tg(Alb-cre)21Mgn/Speer6-ps1^+	involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * DBA