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Caption | Histological analysis of transgenic prostates. Tissue sections from 1 year-old males with genotypes: Tg(Pbsn-cre)4Prb/0 (PbCre4), Tg(Pbsn-cre)4Prb/0 Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+ (PbCre4;Bmi1LSL), Tg(Pbsn-cre)4Prb/0 Ptentm1Mro/Pten+ (PbCre4;Ptenlox/+), and Tg(Pbsn-cre)4Prb/0 Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+ Ptentm1Mro/Pten+ (PbCre4;Bmi1LSL;Ptenlox/+) were stained with H&E and scored for prostate lesions. Mice harboring a given type of lesion often displayed the whole panel of lower grade lesions. Images are from one representative mouse per genotype for consistency. Scale bar: 100 um. Insets: 5-fold higher-power views. | ||||||||
Copyright | This image is from Nacerddine K, J Clin Invest 2012 May 1;122(5):1920-32 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184533 | ||||||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/24/2024 MGI 6.24 |
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