Phenotype Image Detail

Image

Caption

Pik3ca^tm1.1Waph in the ovarian surface epithelium leads to hyperproliferative changes. (i) Non-AdCre exposed ovary from Pik3ca^tm1.1Waph/Pik3ca^tm1.1Waph (Pik3ca^H1047R) mutant mouse 12 months post AdCre, mag x4 (i). AdCre exposed ovary from mutant mice 12 months post AdCre from mouse 1 (ii and iii), mouse 2 (iv and v) and mouse 3 (vi and vii) at mag x4 (ii, iv and vi) and x20 (iii, v and vii).

Copyright

This image is from Kinross KM, J Clin Invest 2012 Feb 1;122(2):553-7 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184382

Associated Alleles

Symbol	Name
Pik3ca^tm1.1Waph	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1.1, Wayne A Phillips

Associated Genotypes

Allelic Composition	Genetic Background
Pik3ca^tm1.1Waph/Pik3ca^+	involves: 129S1/Sv * C57BL/6