Image |
|
||||
Caption | Patent foramen ovale, aortic valve stenosis and pulmonary valve stenosis in Gata4tm1Grg/Gata4+ (Gata4 G295Ski/wt) murine hearts by histologic section. Interatrial communication in the form of patent foramen ovale (arrowhead in B,D) is found in heterozygous mutant mice (B,D) as compared to wild-type littermate (A,C). (C,D) represent high magnification image of boxed area in (A,B), respectively. Thickening of aortic valve leaflets is found in heterozygous mutant mouse (F) that had aortic valve stenosis by echocardiogram as compared to wild-type (E). Thickened pulmonary valve leaflets in heterozygous mutant mouse are shown (H) as compared to normal leaflets in wild-type littermate (G). RA, right atrium; LA, left atrium; RV, right ventricle; LV, left ventricle; AO, aorta; PA, pulmonary artery. Scale bars indicate 200 um. | ||||
Copyright | This image is from Misra C, PLoS Genet 2012 May;8(5):e1002690, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:185124 | ||||
Associated Alleles |
|
||||
Associated Genotypes |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 08/02/2024 MGI 6.24 |
![]() |
|