Image |
|
||||||
Caption | Mecp2 deficiency results in placenta abnormalities. The top panels (a-d) show placenta stained with hematoxylin and eosin. The inset shows the section at higher magnification. Arrows show apoptotic cells. The middle panels (e-h) show TUNEL staining of the same sections. Apoptotic nuclei appear as multiple spots (yellow) indicating DNA fragmentation. Propidium iodide was used as a counterstain. An increase the number of TUNEL-positive cells and cleaved caspase 3-positive cells was observed in the placentas of Mecp2tm1.1Mitoh/Mecp2+ (Xe2-Xwt--female) and Mecp2tm1.1Mitoh/Y (Xe2-Y-male) embryos having a maternal Mecp2tm1.1Mitoh allele. | ||||||
Copyright | This image is from Itoh M, J Biol Chem 2012 Apr 20;287(17):13859-67 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:184364 | ||||||
Associated Alleles |
|
||||||
Associated Genotypes |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 08/27/2024 MGI 6.24 |
![]() |
|