Phenotype Image Detail

Image

Caption

Cardiac structure in Adra2b^tm1Gsb/Adra2b^tm1Gsb (Adra2b-/-)) mice on postnatal day 0. h and i, frontal sections through hearts on day P0 revealed normal cardiac structure (hematoxylin and eosin staining; bars, 500 um) and closure of the ductus arteriosus (A, aorta; DA, ductus arteriosus (arrow); LV, left ventricle; RV, right ventricle). However, the right ventricle is significantly dilated.

Copyright

This image is from Haubold M, J Biol Chem 2010 Oct 29;285(44):34213-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166788

Associated Alleles

Symbol	Name
Adra2b^tm1Gsb	adrenergic receptor, alpha 2b; targeted mutation 1, Gregory S Barsh

Associated Genotypes

Allelic Composition	Genetic Background
Adra2b^tm1Gsb/Adra2b^tm1Gsb	B6.129-Adra2b^tm1Gsb