Phenotype Image Detail

Image

Caption

Characterization of Atmin^tm1Axbe/Atmin^tm1Axbe Tg(Nes-cre)1Kln/0 (ATMIN^deltaN) mice. B, representative pictures of control Atmin^tm1Axbe/Atmin^tm1Axbe (ATMIN^F/F) and mutant (ATMIN^deltaN) mice at 3 months of age demonstrating severe growth retardation. E, sections through the substantia nigra pars compacta of control and mutant mice were stained with anti-tyrosine hydroxylase antibody to measure the number of dopaminergic neurons in this region. The density of tyrosine hydroxylase-positive cells was counted and corrected using Abercrombie correction.

Copyright

This image is from Kanu N, J Biol Chem 2010 Dec 3;285(49):38534-42 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:167331

Associated Alleles

Symbol	Name
Atmin^tm1Axbe	ATM interactor; targeted mutation 1, Axel Behrens
Tg(Nes-cre)1Kln	transgene insertion 1, Rudiger Klein

Associated Genotypes

Allelic Composition	Genetic Background
Atmin^tm1Axbe/Atmin^tm1Axbe Tg(Nes-cre)1Kln/0	involves: C57BL/6 * SJL