Phenotype Image Detail

Image

Caption

(D,E) At E18.5 many Vangl2^tm1.2Mdea/Vangl2^tm1.2Mdea (vangl2^{deltaTMs/deltaTMs}) fetuses have craniorachischisis. (F,G) Representative images of the posterior tail region that demonstrate the milder spina bifida defects that occur in 26% of mutant embryos. Arrowheads mark the position of the tail (D-G) and brackets mark the length of the open neural tube (E,G).

Copyright

This image is from Yin H, PLoS One 2012;7(2):e31988, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:185311

Associated Alleles

Symbol	Name
Vangl2^tm1.2Mdea	VANGL planar cell polarity 2; targeted mutation 1.2, Michael R Deans

Associated Genotypes

Allelic Composition	Genetic Background
Vangl2^tm1.2Mdea/Vangl2^tm1.2Mdea	B6NCrl.129S6(Cg)-Vangl2^tm1.2Mdea