Phenotype Image Detail

Image

Caption

(C-H) Variable mandible defects in Chrd^tm1Emdr/Chrd^tm1Emdr (Chrd-/-) mutant at late gestation stages compared to wild-type mice (C, E, G). (D) Mild mandible outgrowth defect in Chrd-/- mutant embryo on a C57BL/6 background (arrowhead). (F,H) Total absence of mandibular elements accompanying incomplete midline structure (arrowhead) is displayed in lateral (F) and ventral view (H) of Chrd-/- mutant embryo on a 129S6 congenic background.

Copyright

This image is from Choi M, PLoS Genet 2009 Feb;5(2):e1000395, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:146769

Associated Alleles

Symbol	Name
Chrd^tm1Emdr	chordin; targeted mutation 1, EM De Robertis

Associated Genotypes

Allelic Composition	Genetic Background
Chrd^tm1Emdr/Chrd^tm1Emdr	129S6.129-Chrd^tm1Emdr