Phenotype Image Detail

Image

Caption

(C) Spleen (a and b) and hepatic (c and d) sections from 16 week old wild-type (Hmox^+/+) and Hmox1^tm1.2Gkl/Hmox1^tm1.2Gkl (Hmox^D/D) mice stained with H&E. Mutants show a progressive chronic inflammatory disease characterized by enlarged spleens and hepatic inflammatory lesions. Bars, 100 uM.

Copyright

This image is from Tzima S, J Exp Med 2009 May 11;206(5):1167-79, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:148498

Associated Alleles

Symbol	Name
Hmox1^tm1.2Gkl	heme oxygenase 1; targeted mutation 1.2, George Kollias

Associated Genotypes

Allelic Composition	Genetic Background
Hmox1^tm1.2Gkl/Hmox1^tm1.2Gkl	involves: 129 * BALB/cJ * C57BL/6