Phenotype Image Detail

Image

Caption

Impaired outgrowth of Nelfb^tm1.2Roli/Nelfb^tm1.2Roli (-/-) blastocysts. A. In vitro developed blastocysts from two-cell stage embryos. B. Nelfb deletion resulted in elevated incidence of outgrowths with defective or no ICM derivatives. C-D. Normal (Cobra+/+; C) and defective (Cobra-/-; D) blastocyst outgrowth four days after in vitro culture. The ICM derivatives (*) and trophoblast giant cells (TGC) are indicated.

Copyright

This image is from Amleh A, PLoS ONE 2009;4(4):e5034, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:148508

Associated Alleles

Symbol	Name
Nelfb^tm1.2Roli	negative elongation factor complex member B; targeted mutation 1.2, Rong Li

Associated Genotypes

Allelic Composition	Genetic Background
Nelfb^tm1.2Roli/Nelfb^tm1.2Roli	involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N