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Caption | Bone development in Ptpn2tm1Mtr/Ptpn2tm1Mtr (Ptpn2-/-; BALB/c) mice. Representative longitudinal sections of tibiae from (a) 14 day-old Ptpn2tm1Mtr/Ptpn2tm1Mtr (Ptpn2-/-; BALB/c), Ptpn2tm1Mtr/Ptpn2tm1Mtr (Ptpn2-/-; C57BL/6) and Ptpn2tm2.1Ttig/Ptpn2tm2.1Ttig (Ptpn2ex2-/ex2-) mice, or (b) 21 day-old Ptpn2-/- (BALB/c) and Ptpn2ex2-/ex2- mice and their corresponding littermate wild-type controls stained with the von Kossa technique (mineralized bone stained black). In a) safranin O staining [only shown for 14 day-old Ptpn2+/+ (BALB/c) and Ptpn2-/- (BALB/c)] highlights the delayed cartilage (in orange) destruction; scale bar = 100 micron. | ||||||||
Copyright | This image is from Wiede F, PLoS One 2012;7(5):e36703, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:186843 | ||||||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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