Phenotype Image Detail

Image

Caption

Histological analysis of kidneys revealing nephrocalcinosis in Cldn10^tm1.1Dmu/Cldn10^tm1.1Dmu Tg(Cdh16-cre)91Igr/0 kidneys (A, B, and D) compared with kidneys from control mice (C and E). Von Kossa (A-C) and alizarin red S (D and E) staining show a characteristic calcification pattern in both stripes of the outer medulla in mutant kidney sections. (Scale bars: 1 mm in A-C; 0.4 mm in D and E).

Copyright

This image is from Breiderhoff T, Proc Natl Acad Sci U S A 2012 Aug 28;109(35):14241-6. Copyright 2012 National Academy of Sciences, U.S.A. J:188580

Associated Alleles

Symbol	Name
Cldn10^tm1.1Dmu	claudin 10; targeted mutation 1.1, Dominik Muller
Tg(Cdh16-cre)91Igr	transgene insertion 91, Peter Igarashi

Associated Genotypes

Allelic Composition	Genetic Background
Cldn10^tm1.1Dmu/Cldn10^tm1.1Dmu Tg(Cdh16-cre)91Igr/0	involves: C57BL/6 * ICR * SJL