Phenotype Image Detail

Image

Caption

Greater bone mass in Pyy^tm1(cre)Hhzg/Pyy^tm1(cre)Hhzg (PYY-/-) mice. Representative images of distal femur histological sections and 3D surface rendered models of mCT scanned lumbar vertebra of male (C) and female (D) mice showing greater cancellous bone volume in the distal femoral metaphysis of the mutant mice in both genders and in the lumbar vertebral body of female mutant mice (D). Mean +/- SEM of 7-18 mice per group are shown. *p < 0.05; **88p < 0.005 versus wild-type (WT).

Copyright

This image is from Wong IP, PLoS One 2012;7(7):e40038, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:189512

Associated Alleles

Symbol	Name
Pyy^tm1(cre)Hhzg	peptide YY; targeted mutation 1, H Herzog

Associated Genotypes

Allelic Composition	Genetic Background
Pyy^tm1(cre)Hhzg/Pyy^tm1(cre)Hhzg	involves: 129