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Phenotype Image Detail
Image
Caption Morphological and vascular abnormalities in male hemizygous Atp7atm1.1Mjp/Y Cldn6tm1(cre)Dkwu/Cldn6+ (Atp7afl/Y; Clnd6Cre+/-) embryos. A) Developmental anomalies particularly in the frontonasal region and tail bud orientation were apparent in the mutant male embryos at E10.5. B) The blood-filled vascular network observed in wild-type embryos (Atp7a=/Y;Cldn6Cre+/-) and yolk sacs (arrowheads) was lacking for the mutant.
Copyright This image is from Wang Y, PLoS One 2012;7(8):e43039, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:189931
Associated
Alleles
Symbol Name
Atp7atm1.1Mjp ATPase, copper transporting, alpha polypeptide; targeted mutation 1.1, Michael J Petris
Cldn6tm1(cre)Dkwu claudin 6; targeted mutation 1, Doris Wu
Associated
Genotypes
Allelic Composition Genetic Background
Atp7atm1.1Mjp/Y
Cldn6tm1(cre)Dkwu/Cldn6+
involves: C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory