Phenotype Image Detail

Image

Caption

The progressive increase in the number of Kupffer cells (F4/80 antibody) and the activation of hepatic stellate cells (HSCs) near the portal regions (Sirius red staining and anti-desmin antibody) in Mir122^tm1.1Apts/Mir122^tm1.1Apts (Mir122a-/-) livers. Scale bars: 100 um, 50 um (insets), and 20 um (insets, desmin). n = 6.

Copyright

This image is from Tsai WC, J Clin Invest 2012 Aug 1;122(8):2884-97 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:190066

Associated Alleles

Symbol	Name
Mir122^tm1.1Apts	microRNA 122; targeted mutation 1.1, Ann-Ping Tsou

Associated Genotypes

Allelic Composition	Genetic Background
Mir122^tm1.1Apts/Mir122^tm1.1Apts	involves: 129 * C57BL/6