Phenotype Image Detail

Image

Caption

Female Mir122^tm1.1Apts/Mir122^tm1.1Apts (mir-122-/-) mice developed hepatic fibrosis (Sirius Red), inflammation (F4/89 for Kupffer cells) and accumulated less glycogen (PAS staining) as seen in the male mutant mice.

Copyright

This image is from Tsai WC, J Clin Invest 2012 Aug 1;122(8):2884-97 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:190066

Associated Alleles

Symbol	Name
Mir122^tm1.1Apts	microRNA 122; targeted mutation 1.1, Ann-Ping Tsou

Associated Genotypes

Allelic Composition	Genetic Background
Mir122^tm1.1Apts/Mir122^tm1.1Apts	involves: 129 * C57BL/6