Phenotype Image Detail

Image

Caption

Mir378a^tm1.1Eno/Mir378a^tm1.1Eno (KO) mice are resistant to high-fat diet (HFD)-induced obesity. (D) (Left) Subcutaneous fat pads from knock-out (KO) and wild-type (WT) mice. (Middle and Right) H&E-stained histological sections of visceral fat pads from KO and WT mice after 8 weeks of HFD. Pictures were taken using the rhodamine channel on a Leica DMRXE fluorescent microscope. (Scale bars: 100 um.) (F) (Left) Liver from KO and WT mice after 8 weeks of HFD. (Middle and Right) Oil red O staining of histological liver sections from WT and KO mice after 8 weeks of HFD. (Scale bar: 20 um.)

Copyright

This image is from Carrer M, Proc Natl Acad Sci U S A 2012 Sep 18;109(38):15330-5. Copyright 2012 National Academy of Sciences, U.S.A. J:190154

Associated Alleles

Symbol	Name
Mir378a^tm1.1Eno	microRNA 378a; targeted mutation 1.1, Eric N Olson

Associated Genotypes

Allelic Composition	Genetic Background
Mir378a^tm1.1Eno/Mir378a^tm1.1Eno	involves: 129S/SvEv * C57BL/6