Phenotype Image Detail

Image

Caption

Mir122^tm1.1Kgh/Mir122^tm1.1Kgh (Mir122 KO) mice develop hepatitis and fibrosis with age. (C) Portal inflammation, steatosis, and fibrosis in 6-month-old mutant mice. Eight to 10 mice of each genotype were analyzed after overnight fasting. Scale bars for C: top row, 200 um; middle row, 25 um; bottom row, 100 um.

Copyright

This image is from Hsu SH, J Clin Invest 2012 Aug 1;122(8):2871-83 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:190067

Associated Alleles

Symbol	Name
Mir122^tm1.1Kgh	microRNA 122; targeted mutation 1.1, Kalpana Ghoshal

Associated Genotypes

Allelic Composition	Genetic Background
Mir122^tm1.1Kgh/Mir122^tm1.1Kgh	involves: 129S1/Sv * 129X1/SvJ