Phenotype Image Detail

Image

Caption

Camk2d^tm1.1Jhb/Camk2d^tm1.1Jhb (KO) mice have reduced relative heart weight (HW) and lung edema in response to 6-week transverse aortic constriction (TAC). HW and lung weight (LW) were normalized to body weight (BW) and tibial length (TL). Data are mean +/- SEM of values from 3-9 mice. *P < 0.05, **P < 0.01 versus sham; #P < 0.05, ##P < 0.01 versus wild-type TAC.

Copyright

This image is from Ling H, J Clin Invest 2009 May;119(5):1230-40 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:149675

Associated Alleles

Symbol	Name
Camk2d^tm1.1Jhb	calcium/calmodulin-dependent protein kinase II, delta; targeted mutation 1.1, Joan Heller Brown

Associated Genotypes

Allelic Composition	Genetic Background
Camk2d^tm1.1Jhb/Camk2d^tm1.1Jhb	involves: 129S4/SvJae * Black Swiss