Phenotype Image Detail

Image

Caption

Severe hemorrhaging in Rr249^tm1.1Ebres/Rr249^tm1.1Ebres embryos. (D) Representative E13.5 wild-type (+/+), Rr249^tm1.1Ebres/Rr249^tm1.1Ebres (-/-), and Rr249^tm1.1Ebres/Gata2⁺ (+/-) littermates. (E) Subcutaneous hemorrhage in the trunk (left) and in the brain ventricular space (right) in homozygous mutant embryos detected by H&E staining of transverse sections. Scale bars: 50 uM.

Copyright

This image is from Johnson KD, J Clin Invest 2012 Oct 1;122(10):3692-704 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:191756

Associated Alleles

Symbol	Name
Rr249^tm1.1Ebres	regulatory region 249; targeted mutation 1.1, Emery H Bresnick

Associated Genotypes

Allelic Composition	Genetic Background
Rr249^tm1.1Ebres/Rr249^tm1.1Ebres	involves: 129 * BALB/cJ * C57BL/6