Phenotype Image Detail

Image

Caption

Postnatal development of cystic kidney in Pkd1^tm1.1Fqi/Pkd1^tm1.1Fqi (V/V) mice. General appearance of the mice and their kidneys at P9 (A) and P16 (B). Note that Pkd1^tm1.1Fqi/Pkd1^tm1.1Fqi kidneys are enlarged, pale, and cystic compared with kidneys from wild-type (WT) and heterozygous (V/+) littermates.

Copyright

This image is from Yu S, Proc Natl Acad Sci U S A 2007 Nov 20;104(47):18688-93. Copyright 2007 National Academy of Sciences, U.S.A. J:127628

Associated Alleles

Symbol	Name
Pkd1^tm1.1Fqi	polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Feng Qian

Associated Genotypes

Allelic Composition	Genetic Background
Pkd1^tm1.1Fqi/Pkd1^tm1.1Fqi	B6.129S6-Pkd1^tm1.1Fqi