Phenotype Image Detail

Image

Caption

B cell lymphomas developed in Trp53^tm1Yjc/Trp53^tm1Yjc (p53^rev/rev) mice. C, E, G, I) Structure of splenic marginal zone for normal C57BL/6, normal mutant, and two individual tumor-bearing mutant mice, respectively (H&E, 10X). D, F, H, J) High magnification of red pulp of and marginal zone for the spleen of a normal C57BL/6 mouse, normal mutant, and lymphoma-affected spleens from two different mutant mice, respectively (H&E, 63X).

Copyright

This image is from Chiang YJ, PLoS One 2012;7(11):e49305, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195018

Associated Alleles

Symbol	Name
Trp53^tm1Yjc	transformation related protein 53; targeted mutation 1, Y Jeffrey Chiang

Associated Genotypes

Allelic Composition	Genetic Background
Trp53^tm1Yjc/Trp53^tm1Yjc	B6.129S1-Trp53^tm1Yjc