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Caption | Few Purkinje cells (PCs) survive in 12 week old Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 (Afg312PC-KO) mice. Vibratome sections of the cerebellum at 12 weeks from Afg3l2tm1Arte/Afg3l2tm1Arte (Afg312fl/fl) and Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 mice and stained for calbindin (A, B) to show PC loss. IBA1 (C, D) to detect resting and activated microglia, and glial fibrillary protein (GFAP) (E, F) to mark reactive astrocytes. Scale bars: 200 um (A, B), 50 um (C, D), 100 um (E, F). | ||||||
Copyright | This image is from Almajan ER, J Clin Invest 2012 Nov 1;122(11):4048-58 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193564 | ||||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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